Synchronized and controlled release of metformin hydrochloride/glipizide from elementary osmotic delivery
نویسندگان
چکیده
منابع مشابه
Controlled Release Drug Delivery from Hydrogels
The objective of this project is to introduce students to the concepts of diffusion, polymers and polymerization reactions, and enzyme mediated reactions by designing and testing a controlled release drug delivery system. These types of systems are also referred to as localized drug delivery because an implant that releases drugs is placed directly into diseased tissue. Here, we use Jell-O c ©a...
متن کاملDrug Delivery: Controlled Release
Over the past decades, the treatment of illness has been accomplished by administering drugs to the human body via various pharmaceutical dosage forms, like tablets. These traditional pharmaceutical products are still commonly seen today in the prescription and over-the-counter drug marketplace. To achieve and maintain the drug concentration in the body within the therapeutic range required for...
متن کاملOsmotic Controlled Drug Delivery System: A Review
Department of Pharmaceutics, Hindu College of Pharmacy, Guntur, Andhra Pradesh, India. _______________________________________________________________________ ABSTRACT Conventional drug delivery systems have slight control over their drug release and almost no control over the effective concentration at the target site. This kind of dosing pattern may result in constantly changing, unpredictabl...
متن کاملDesign and Evaluation of Delayed-Release Osmotic Capsule of Acetaminophen
Hard gelatin capsule filled with acetaminophen, osmotic agent (sorbitol), a release promoter (sodium dodecyl sulfate), coated with a semipermeable cellulose acetate membrane containing a hydrophobic plasticizer (castor oil) and sealed with white bees wax plug was designed. When placed in the sink water penetrates the membrane, dissolves the osmotic agent and increases the osmotic pressure...
متن کاملFormulation and Evaluation of Glibenclamide Osmotic Controlled Drug Delivery Systems
The objective of the study was to develop Controlled porosity and elementary osmotic pump-based drug delivery systems of Glibenclamide. The elementary osmotic pump (EOP) consists of an osmotic core with the drug surrounded by a semipermeable membrane drilled with a delivery orifice through which drug releases where as in controlled porosity osmotic pump drug release is accomplished by the use o...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Drug Development and Industrial Pharmacy
سال: 2016
ISSN: 0363-9045,1520-5762
DOI: 10.1080/03639045.2016.1200071